Focused SNP Genotyping

CynerGene provides focused SNP genotyping using Illumina's BeadXpress reader with Veracode technology. Veracode technology leverages the power of digital holographic codes to provide a robust detection method for multiplex assays requiring high precision, accuracy and speed. The BeadXpress platform is based on the GoldenGate assay and can perform 1-384 SNPs per sample. The proven GoldenGate assay combined with the highly regarded Veracode technology on the BeadXpress generate superior quality. We continue to demonstrated high degrees of sample success, locus success, call rates, reproducibility, and heritability in data sets generated at 48, 96, 144, 192, and 384-plex.

 The results confirm that VeraCode technology robustly produces high quality data with the essential properties of a platform designed for accurate performance in low- to mid-level multiplexing and high-throughput SNP genotyping.  Overall most runs achieved outstanding genotyping results.

• Call rates ≥ 99.9%

• Sample success rates = 100%

• Locus success rate ≥ 99% 

 Focused SNP Genotyping projects preformed:

• Pharmacogenomics and Pharmacogenetics – Metabolic profiles for drug research
• Association studies - Targeted and candidate gene studies
• Fine Mapping - Validate by fine mapping of Genome Wide Association Studies (GWAS)
• Cell line QC - Cell lines can be monitored at various time intervals for chromosomal aberrations, deletions and duplications thus assuring stability of cell lines to ensure integrity of future experiments 

 Consultative Process

• Consult with a Biostatistician to help you with initial project design